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Explore the glamorous Mediterranean coast aboard one of our unforgettable cruises from Rome to Greece. There’s a wide variety of sailings to choose from, including itineraries that span from 7 to 12 nights that depart from the early spring until late fall. 

Embark on an 8-night Italy and Greek Islands cruise that stops in popular ports like Santorini and Mykonos, as well as more under-the-radar destinations such as Rhodes and Argostoli. Visit holy sites and ancient ruins during a 12-night Israel and Mediterranean cruise. Or go on a 10-night cruise to the Greek Islands and Malta, where you’ll hop from one idyllic island to the next and witness some of the most spectacular sunsets you’ve ever seen.

Departure Port

Rome

Set sail from the Eternal City, a destination with fascinating architecture, history, and art at every turn. Spend a day or two before your cruise from Rome to Greece discovering the capital of Italy and its many cultural treasures. Go inside the Colosseum and marvel at this open-air amphitheater that dates back over 2,000 years. Toss a coin at the stunning Trevi Fountain, a beautiful Baroque landmark. Or head to Vatican City and stop by iconic sites such as St. Peter’s Basilica and the Sistine Chapel, where you can gaze up at Michelangelo’s magnificent frescoes.

Ports of Call

Athens

On some of our cruises from Rome to Greece, you’ll stop in Athens, the former political and cultural center of Ancient Greece. Learn about art, history, and the origins of democracy by visiting its most famous landmarks, starting with the Acropolis, where you’ll marvel at monuments and temples including the spectacular Parthenon. Then head to the nearby Acropolis Museum and admire a wealth of artifacts that date back to the 5th century BC. Or walk around the picturesque Plaka neighborhood and stroll past colorful houses and blooming bougainvillea before stopping for a delicious meal at an authentic taverna.

Santorini

Experience the magic of the Cyclades islands during a port day in Santorini, a spectacular island surrounded by the sparkling blue Aegean Sea. Make your way around Santorini’s charming villages, like the cliff-top Oia and Fira, where you’ll find endless al fresco restaurants and chic boutiques. Spend the afternoon at the island’s oldest winery sipping a glass of crisp white wine or enjoy a cliffside lunch full of fresh seafood, local meze, and unbeatable views.

Mykonos

Spend a day in exquisite Mykonos, an island known for its lively nightlife and stunning landscapes. Sunbathe at Elia Beach, where you can swim in the cool Mediterranean Ocean. Walk around Ano Mera, a town with white-washed buildings and historic landmarks. Or take a day trip to the island of Delos, which is said to be the birthplace of the twin gods, Apollo and Artemis. 

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