Barcelona to Athens cruises take you right across the sparkling Mediterranean, calling at ports along France’s glamorous Côte d’Azur, the glorious Ligurian coast of Italy, and through the sun-drenched Greek Islands before disembarking in Athens. Take in the art treasures of Florence and the magnificent Colosseum in Rome. Admire the honey-colored ramparts of Valletta, Malta’s capital, and the grand medieval mansions of Rhodes.

Art and architecture aside, this is a voyage through some of Europe’s most exquisite landscapes. Visit the Cinque Terre National Park, where mountains plunge into the sea and tiny villages cling to the cliffs. Relax on the golden sandy beaches that encircle Mykonos. Don’t miss tasting local specialties wherever you go, like tangy limoncello and rainbow-colored gelato in Italy, rich bouillabaisse in Marseille, and flaky spinach and feta pies in Greece.

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Featured Ports of Call

Valletta

Malta’s compact, historic capital spills over the clifftop around a vast, natural harbor, protected by vast walls built by the Knights of St. John in the 16th century. See extraordinary artworks in the opulent Co-Cathedral of St. John, and admire the contemporary City Gate. Take a trip to ancient Mdina, a cluster of medieval churches and palaces, or admire the luminous Blue Grotto on a boat trip. Try the local cuisine, a tasty blend of Sicilian and Arabic influences.

Marseille

Explore France’s oldest city during a day in Marseille. Take in the buzz of the Vieux Port, lined with restaurants offering the city’s famous fish soup, bouillabaisse. Head inland to Avignon, the 14th-century epicenter of the Catholic Church, and visit Palais des Papes, home of seven successive popes. Taste local olive oil and shop for lavender-scented soap from Provence. Enjoy the great outdoors on a cycling trip through the countryside or a kayak expedition along the craggy coast.

Santorini

On the island of Santorini, sugar-cube houses and blue-domed churches cling to the sheer-sided rim of a vast volcano, creating one of the most famous sights in Greece. Shop for jewelry in Fira, the capital, or head to Oia for sweeping views of the caldera and the sapphire-blue sea below. Learn about the sophisticated lifestyle of the Minoans at Akrotiri, an amazing archaeological site dating back 4,000 years, or join a tour to taste the island’s impressive wines.

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